Born in Munich and raised in Spain, Sebastian Klinger received his first cello lessons at the age of 6. He later studied with Heinrich Schiff in Salzburg and Vienna and with Boris Pergamenschikow in Berlin.

After winning numerous national and international awards at various competitions and foundations, he won the German Music Competition in Berlin in 2001. This was followed by debuts at the most important German festivals such as Schleswig-Holstein, Rheingau, Mecklenburg-Vorpommern and Ludwigsburg, as well as multiple recitals at the Concertgebouw Amsterdam. In 2002, on the initiative of the Cologne Philharmonic, he was invited to perform as part of the Rising Stars Series (European Concert Hall Organization), which eventually took him to some of the most important music centers in Europe and the United States (Carnegie Hall New York, Wigmore Hall London, Palais des Beaux-Arts Brussels, Konserthus Stockholm, Konzerthaus Vienna, Concert Hall Athens and others).
Sebastian Klinger now performs as a soloist and chamber musician throughout Europe, Asia, the United States and South Africa, including solo appearances with orchestras such as the Bavarian Radio Symphony Orchestra, the Berlin Radio Symphony Orchestra, the Orchestra of the Accademia Nazionale di Santa Cecilia Rome, the Gulbenkian Orchestra Lisbon, the Munich Chamber Orchestra, the Munich and Hamburg Symphonies, the National Orchestra of the RAI Turin, the Orchestra of the Beethovenhalle Bonn, the Johannesburg Symphony Orchestra, the Staatskapelle Weimar and the German Radio Philharmonic Orchestra. He works with conductors such as Mariss Jansons, Antoni Wit, Christoph Poppen, Michael Sanderling, Pedro Halffter, Oksana Lyniv, Simon Gaudenz, Constantin Trinks and Joshua Weilerstein.
Sebastian Klinger's chamber music partners include Valéry Afanassiev, Kit Armstrong, Yuri Bashmet, Lisa Batiashvili, Milana Chernyavska, Ana Chumachenko, Veronika Eberle, Julia Fischer, Vilde Frang, Christian Gerhaher, Gerold Huber, Janine Jansen, Gidon Kremer, Lang Lang, Francois Leleux, Alexander Lonquich, Yo-Yo Ma, Plamena Mangova, Lena Neudauer, Enrico Pace, Emmanuel Pahud, Alina Pogostkina, Lawrence Power, Herbert Schuch, Gil Shaham, Antoine Tamestit, Alexandre Tharaud, Jörg Widmann, Natalia Prischepenko (Artemis Quartet), Arnold Steinhardt (Guarneri Quartet), the Belcea, the Fauré, the Philharmonia and the Rosamunde Quartets.
His discography, for which he has already been awarded a "Diapason d'Or" (Bach Cello Suites), includes solo works, chamber music and orchestral repertoire on the Oehms Classics, Sony Classical and Deutsche Grammophon labels, among others.
Sebastian Klinger was 1st solo cellist in the Bavarian Radio Symphony Orchestra for twelve years, where he worked with almost all the great conductors of our time, before accepting a call to the cello professorship at the Hochschule für Musik und Theater Hamburg in 2015.